Dokar Vita Cells
Cellular technologies for treatment and health maintenance.
Cell therapy programs
Anti-aging therapy and revitalization
Dokar Vita Active
Dokar Vita Active
Aging is a decrease in the ability of cells to renew themselves and resist external influences (microbes, lifestyle, injuries, environmental and information factors, emotions, etc.). The cause of aging is a decrease in the number of multipotent mesenchymal stromal cells (MMSC) in the body.
The main goals of the Dokar Vita Active revitalization program:
• delay aging and related diseases as much as possible, prolong the active period of life;
• improve performance, appearance, physical fitness;
• treat existing diseases;
• increase adaptation and immune defense capabilities, prevent the development of cancer.
The target audience of the Dokar Vita Active program is people over 40 who understand the value of prevention and investment in themselves.
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with age, replace damaged cells with new ones, form new capillaries, improving blood circulation.
RESULTS:
The main goals of the Dokar Vita Active revitalization program:
• delay aging and related diseases as much as possible, prolong the active period of life;
• improve performance, appearance, physical fitness;
• treat existing diseases;
• increase adaptation and immune defense capabilities, prevent the development of cancer.
The target audience of the Dokar Vita Active program is people over 40 who understand the value of prevention and investment in themselves.
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with age, replace damaged cells with new ones, form new capillaries, improving blood circulation.
RESULTS:
- Improved well-being
- Increased efficiency
- Improved sleep
- Psychological harmonization
- Increased libido
- Normalization of hormone production, liver and heart function
- Improved skin condition
- Improved condition of joints and spine
Treatment of internal diseases with MMSC
Dokar Vita Healing
Dokar Vita Healing
The medical team of Dokar Vita Cells develops a personalized treatment program after a remote consultation (determining the appropriateness of treatment, prognosis, dosage and number of procedures).
With the help of MMSC (multipotent mesenchymal stromal cells), it is possible to achieve an improvement in the condition and complete or partial remission due to the restoration of damaged cells and organs.
TREATMENT PROGRAMS for adults and children:
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with age and chronic diseases, replace damaged cells with new ones, form new capillaries, improving blood circulation, balance the state of the immune system, prevent fibrosis and cell death.
The earlier treatment with MMSCs begins, the better the result.
RESULTS:
With the help of MMSC (multipotent mesenchymal stromal cells), it is possible to achieve an improvement in the condition and complete or partial remission due to the restoration of damaged cells and organs.
TREATMENT PROGRAMS for adults and children:
- Diabetes types 1 and 2;
- Heart diseases: coronary heart disease, cardiomyopathy, myocardial dystrophy, heart failure, rehabilitation after surgery;
- Lung diseases: bronchial asthma, pulmonary fibrosis, EBV and others;
- Liver diseases: chronic hepatitis, cirrhosis, liver failure;
- Diseases of the central and peripheral nervous system: condition after stroke, cerebral palsy, multiple sclerosis, craniocerebral and cerebrovascular accidents and others;
- Treatment of infertility and erectile dysfunction;
- Autoimmune and other diseases;
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with age and chronic diseases, replace damaged cells with new ones, form new capillaries, improving blood circulation, balance the state of the immune system, prevent fibrosis and cell death.
The earlier treatment with MMSCs begins, the better the result.
RESULTS:
- Reduction of manifestation or complete disappearance of the underlying disease
- Reduction of dosage or cessation of use of medications
- Improvement of well-being
- Reduction or cessation of the risk of complications from the underlying disease
Treatment of joint and spine diseases with MMSC (orthopedics)
Dokar Vita Flex
Dokar Vita Flex
ORTHOPEDICS - treatment of joints and spine
MMSCs (multipotent mesenchymal stromal cells) produce cytokines and regeneration factors that activate the formation of new cells to replace destroyed ones (cartilage cells, ligaments, etc.).
Regeneration factors and exosomes (more than 100) relieve inflammation and activate tissue regeneration, local immunity, collagen production, stimulate capillary growth, improving microcirculation.
Thus, the structure and function of the joint is restored.
During the treatment, taping is used according to our own protocols, which creates optimal conditions for regeneration.
Indications:
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with age and with injuries and chronic degenerative diseases, replace damaged cells with new ones, form new capillaries, improving blood circulation. Stimulate the formation of synovial fluid, improve the condition of cartilage and ligaments.
RESULTS:
MMSCs (multipotent mesenchymal stromal cells) produce cytokines and regeneration factors that activate the formation of new cells to replace destroyed ones (cartilage cells, ligaments, etc.).
Regeneration factors and exosomes (more than 100) relieve inflammation and activate tissue regeneration, local immunity, collagen production, stimulate capillary growth, improving microcirculation.
Thus, the structure and function of the joint is restored.
During the treatment, taping is used according to our own protocols, which creates optimal conditions for regeneration.
Indications:
- Chronic joint diseases of post-traumatic, degenerative and autoimmune origin;
- Back and joint pain in adults and children;
- Damage to ligaments, menisci, intervertebral discs;
- To speed up recovery after surgery and injuries
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with age and with injuries and chronic degenerative diseases, replace damaged cells with new ones, form new capillaries, improving blood circulation. Stimulate the formation of synovial fluid, improve the condition of cartilage and ligaments.
RESULTS:
- Improvement of the condition or complete restoration of the joint
- Restoration of functionality and mobility of joints or spine
- Disappearance or reduction of pain syndrome
Facial care with MMSC (cosmetology)
Dokar Vita Beauty
Dokar Vita Beauty
COSMETOLOGY - beauty injections
MMSCs (multipotent mesenchymal stromal cells) restore the activity and quantity of fibroblasts that produce collagen, elastin and hyaluronic acid, thereby reducing wrinkles and making the skin fresher and more elastic.
In addition, the cells produce a cascade of biologically active substances (exosomes, growth factors, peptides, signaling molecules, immune complexes, etc.).
MMSCs produce cytokines and regeneration factors that activate the formation of new cells to replace destroyed ones.
Regeneration factors and exosomes (more than 100) relieve inflammation and activate tissue regeneration, local immunity, collagen production, stimulate capillary growth, improving microcirculation.
In the process of stem cell mesotherapy, Beauty taping is used according to our own protocols, which creates optimal conditions for revitalization.
Mesotherapy (local injections) with stem cells (MMSC) is used for:
RESULTS:
MMSCs (multipotent mesenchymal stromal cells) restore the activity and quantity of fibroblasts that produce collagen, elastin and hyaluronic acid, thereby reducing wrinkles and making the skin fresher and more elastic.
In addition, the cells produce a cascade of biologically active substances (exosomes, growth factors, peptides, signaling molecules, immune complexes, etc.).
MMSCs produce cytokines and regeneration factors that activate the formation of new cells to replace destroyed ones.
Regeneration factors and exosomes (more than 100) relieve inflammation and activate tissue regeneration, local immunity, collagen production, stimulate capillary growth, improving microcirculation.
In the process of stem cell mesotherapy, Beauty taping is used according to our own protocols, which creates optimal conditions for revitalization.
Mesotherapy (local injections) with stem cells (MMSC) is used for:
- Revitalization;
- Slowing down the skin aging process (anti-aging);
- Improving the condition of facial skin (color, elasticity);
- Restoring the number and activity of fibroblasts;
RESULTS:
- Improvement of elasticity and color of facial skin;
- Reduction of wrinkles;
- Slowing down the skin aging process (anti-aging);
- Restoration of the number and activity of fibroblasts;
- Lifting effect;
Use of MMSC in professional sports
Dokar Vita Sport
Dokar Vita Sport
Cell Therapy for Professional Sports
When doing professional sports, the body is subjected to high, sometimes excessive loads and is accompanied by frequent injuries.
The main health problems of professional athletes:
1. Injuries
2. Overfatigue and overtraining
3. High, excessive loads on the heart
4. Stress
Such loads do not pass without a trace and, as a rule, affect health in the future. Many professional athletes become disabled. There are almost no professional athletes among long-livers.
The main goals of the Dokar Vita Sport program:
The target audience of the Dokar Vita Active program is professional athletes who understand the value of disability prevention and investing in their health.
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with high loads (depletion of reserves), replace damaged cells with new ones, form new capillaries, improving blood circulation, and balance the state of the immune system.
RESULTS:
When doing professional sports, the body is subjected to high, sometimes excessive loads and is accompanied by frequent injuries.
The main health problems of professional athletes:
1. Injuries
2. Overfatigue and overtraining
3. High, excessive loads on the heart
4. Stress
Such loads do not pass without a trace and, as a rule, affect health in the future. Many professional athletes become disabled. There are almost no professional athletes among long-livers.
The main goals of the Dokar Vita Sport program:
- Rapid treatment of injuries;
- Maintaining a high level of endurance;
- Protecting the heart and brain from damage during high loads;
- Accelerated recovery after loads or competitions.
The target audience of the Dokar Vita Active program is professional athletes who understand the value of disability prevention and investing in their health.
Mechanism of action - MMSCs restore the synthesis of hormones and biologically active substances, the production of which decreases with high loads (depletion of reserves), replace damaged cells with new ones, form new capillaries, improving blood circulation, and balance the state of the immune system.
RESULTS:
- Improved well-being. Increased endurance and recovery.
- Improved sleep.
- Psychological harmonization.
- Increased attention and concentration.
- Normalization of hormone production, liver, heart, and brain function.
- Acceleration of recovery after injuries.
- Improved condition of joints and spine.
Oncology treatment
Treatment of oncological diseases
The medical team of Dokar Vita Cells develops a personalized treatment program after a remote consultation (determining the appropriateness of treatment, prognosis, dosage and number of procedures).
Oncological treatment includes the use of MMSC (multipotent mesenchymal stem cells), oncolytic viruses and donor NK cells. Thanks to this, it is possible to achieve an improvement in the condition and complete or partial remission due to the activation of the anti-cancer defense of the immune system, destruction of the tumor and restoration of damaged cells and organs.
MMSCs restore the synthesis of hormones and biologically active substances, replace damaged cells with new ones, form new capillaries, improving blood circulation, activate anti-cancer immunity, prevent fibrosis and cell death.
Oncolytic viruses destroy the tumor and attract the attention of the immune system, activating its own dendritic and NK (natural killer) cells, as well as T-lymphocytes. The type of oncolytic viruses is selected individually for each patient depending on the type of tumor, stage and condition of the patient. The treatment program usually includes intravenous and local administration of oncolytic viruses.
Donor NK cells directly destroy cancer cells. Their introduction increases the total number of NK cells in the body several times.
The earlier treatment begins, the greater the chance of a complete cure.
RESULTS:
Oncological treatment includes the use of MMSC (multipotent mesenchymal stem cells), oncolytic viruses and donor NK cells. Thanks to this, it is possible to achieve an improvement in the condition and complete or partial remission due to the activation of the anti-cancer defense of the immune system, destruction of the tumor and restoration of damaged cells and organs.
MMSCs restore the synthesis of hormones and biologically active substances, replace damaged cells with new ones, form new capillaries, improving blood circulation, activate anti-cancer immunity, prevent fibrosis and cell death.
Oncolytic viruses destroy the tumor and attract the attention of the immune system, activating its own dendritic and NK (natural killer) cells, as well as T-lymphocytes. The type of oncolytic viruses is selected individually for each patient depending on the type of tumor, stage and condition of the patient. The treatment program usually includes intravenous and local administration of oncolytic viruses.
Donor NK cells directly destroy cancer cells. Their introduction increases the total number of NK cells in the body several times.
The earlier treatment begins, the greater the chance of a complete cure.
RESULTS:
- Slowing or stopping tumor progression.
- Restoring the immune system and anti-cancer defenses.
- Reducing the dosage or stopping the use of chemotherapy.
- Significant improvement in well-being.
- Complete cure.
Modern cellular technologies
For treatment, revitalization, immunomodulation and anti-aging therapy.
MMSC - mesenchymal multipotent stem cells
Mesenchymal multipotent stem cells obtained from the bone marrow of young healthy donors. They have the best regenerative properties. They are used for treatment, revitalization and anti-aging therapy.
Exosomes from stem cells
Exosomes are small vesicles produced by stem cells and containing biologically active substances (growth factors, peptides, cytokines, etc.) to restore damaged cells.
NK cells (natural killers)
NK cells are a type of granular lymphocyte that recognize and destroy tumor and virus-infected cells. They make up 10-15% of all peripheral blood lymphocytes and provide an immediate immune response without the formation of immunological memory. They are used to treat cancer and viral infections.
Oncolytic viruses
OVs have a direct oncolytic effect - they destroy cancer cells by infecting them. In addition, OVs activate T-lymphocytes and help the immune system detect cancer cells. OVs are used to treat cancer and improve the patient's condition after chemotherapy or radiation therapy. OVs combine well with NK cell therapy.
Stem Cells Therapy
Cell therapy has been used since 1995.
ММСК - мультипотентные мезенхимальные стромальные клетки.
THE SECRET OF SUCCESS IN CELL THERAPY
1 - Universal medicine
We are used to the fact that various drugs are used to treat various diseases, and sometimes it is difficult to understand that the same drug is used to treat completely different diseases. This is due to the fact that the action of cells (MMSC) is not aimed at the disease, but at restoring the body's ability to regenerate and resist the disease. Like vitamins, MMSC cells act on the entire body, helping it to cope with the disease and restore lost functions.
2 - Diagnostics and treatment
Multipotent mesenchymal stromal cells (MMSC) have unique properties, one of the most important of which is pathotropism - their ability to independently find foci of damage and inflammation in the body, fix themselves there and begin "repairs". The mechanism of pathotropism is based on the fact that any pathological focus in the body produces proteins of damage or inflammation, and cells (MMSC) have receptors for these proteins. Like a predator following a trail, MMSCs “catch” these proteins in the body and are fixed at the sites of damage. Thus, MMSCs not only perform treatment, but also diagnostics and independently find diseases that tests and symptoms may still “keep silent”.
3 - Holistic approach
The cells affect the entire body as a whole, restoring its functions and blood circulation, activating protection and regeneration.
4 - Natural mechanism
Cell therapy is a natural method of treatment based on natural, genetically programmed mechanisms.
1 - Universal medicine
We are used to the fact that various drugs are used to treat various diseases, and sometimes it is difficult to understand that the same drug is used to treat completely different diseases. This is due to the fact that the action of cells (MMSC) is not aimed at the disease, but at restoring the body's ability to regenerate and resist the disease. Like vitamins, MMSC cells act on the entire body, helping it to cope with the disease and restore lost functions.
2 - Diagnostics and treatment
Multipotent mesenchymal stromal cells (MMSC) have unique properties, one of the most important of which is pathotropism - their ability to independently find foci of damage and inflammation in the body, fix themselves there and begin "repairs". The mechanism of pathotropism is based on the fact that any pathological focus in the body produces proteins of damage or inflammation, and cells (MMSC) have receptors for these proteins. Like a predator following a trail, MMSCs “catch” these proteins in the body and are fixed at the sites of damage. Thus, MMSCs not only perform treatment, but also diagnostics and independently find diseases that tests and symptoms may still “keep silent”.
3 - Holistic approach
The cells affect the entire body as a whole, restoring its functions and blood circulation, activating protection and regeneration.
4 - Natural mechanism
Cell therapy is a natural method of treatment based on natural, genetically programmed mechanisms.
Внутривенная инфузия ММСК
INDICATIONS FOR CELL THERAPY
1 - Revitalization and Anti-Aging
2 - Treatment programs for adults and children
3 - Orthopedics treatment of joints and spine
4 - Cosmetology - mesotherapy (local injections) with stem cells
1 - Revitalization and Anti-Aging
- To improve well-being and increase performance
- To slow down the aging process
- To restore hormonal balance
- To increase endurance and strength in sports
- To restore immunity
2 - Treatment programs for adults and children
- Diabetes types 1 and 2;
- Heart diseases: coronary heart disease, cardiomyopathy, myocardial dystrophy, heart failure, rehabilitation after surgery;
- Lung diseases: bronchial asthma, pulmonary fibrosis, EBV;
- Kidney diseases;
- Liver diseases: chronic hepatitis, cirrhosis, liver failure;
- Diseases of the central and peripheral nervous system: condition after a stroke, cerebral palsy, multiple sclerosis, CM and SM injuries and others;
- Treatment of infertility and erectile dysfunction;
- Autoimmune and other diseases;
3 - Orthopedics treatment of joints and spine
- Chronic joint diseases of post-traumatic, degenerative and autoimmune origin;
- Back and joint pain in adults and children;
- Damage to ligaments, menisci, intervertebral discs;
- To speed up recovery after surgery and trauma
4 - Cosmetology - mesotherapy (local injections) with stem cells
- Revitalization;
- Slowing down the skin aging process (anti-aging);
- Improving the condition of facial skin (color, elasticity);
- Restoring the number and activity of fibroblasts;
Культивирование ММСК в лаборатории
Allogeneic (donor) multipotent mesenchymal stromal cells (Al-MMSC) from bone marrow
For therapy, we use MMSCs obtained from the bone marrow of young and healthy donors. Compared to one's own (autologous) cells, donor cells have a significantly more pronounced effect on treatment and revitalization.
All donors are healthy young people aged 18-25. Dokar selects donors independently. Donors must not smoke, drink alcohol or use drugs. They must not have tattoos (tattoos significantly reduce the activity of MSCs).
Before collecting bone marrow, donors undergo a full examination of the body. Bone marrow is taken from the iliac bone in an amount of no more than 100 ml. The procedure is performed under local anesthesia (ultracaine) and is painless. The donor feels well.
Pure cells (MMSCs) are isolated from the bone marrow and tested for safety and activity. Then the pure fraction of MMSC is placed in a nutrient medium and grown under certain conditions (temperature, pressure, lighting, concentration of O2 and CO2) for 5-7 days.
For therapy, we use MMSCs obtained from the bone marrow of young and healthy donors. Compared to one's own (autologous) cells, donor cells have a significantly more pronounced effect on treatment and revitalization.
All donors are healthy young people aged 18-25. Dokar selects donors independently. Donors must not smoke, drink alcohol or use drugs. They must not have tattoos (tattoos significantly reduce the activity of MSCs).
Before collecting bone marrow, donors undergo a full examination of the body. Bone marrow is taken from the iliac bone in an amount of no more than 100 ml. The procedure is performed under local anesthesia (ultracaine) and is painless. The donor feels well.
Pure cells (MMSCs) are isolated from the bone marrow and tested for safety and activity. Then the pure fraction of MMSC is placed in a nutrient medium and grown under certain conditions (temperature, pressure, lighting, concentration of O2 and CO2) for 5-7 days.
Мультипотентность ММСК - способность превращаться (дифференцироваться) в специализированные клетки организма
Bone Marrow
Bone marrow (BM) is the only human tissue that contains a large number of regenerative cells. Bone marrow is a reserve supply of stromal cells for natural regeneration and emergency recovery of the body (in case of injuries or acute diseases). There are two types of cells in the bone marrow:
Main properties of bone marrow MMSCs:
Bone marrow (BM) is the only human tissue that contains a large number of regenerative cells. Bone marrow is a reserve supply of stromal cells for natural regeneration and emergency recovery of the body (in case of injuries or acute diseases). There are two types of cells in the bone marrow:
- Hematopoietic (HPC) - can transform into blood cells (erythrocytes, leukocytes and platelets)
- Mesenchymal multipotent (stromal, (MMSC)) - can transform into most types of cells.
Main properties of bone marrow MMSCs:
- Regeneration. Bone marrow performs all regeneration in the body. This mechanism is created by nature.
- Regulation and control. Bone marrow mesenchymal cells control the activity of hematopoietic and local progenitor cells. If necessary, they can activate them and transform into them.
- Multipotency is the ability to transform into almost all cells in the body.
- Maturity. Mesenchymal stromal cells are adult resistant cells. Unlike embryonic and umbilical cord stem cells, they are absolutely safe.
Возрастное уменьшение количества ММСК
Age and regeneration
As a result of natural aging, diseases, degeneration, injuries, the number and activity of BM-MMSC (bone marrow mesenchymal stromal stem cells) decreases and the body's ability to self-renew worsens. By the age of 50, the number of MMSC decreases by 20 times, by 75 - 100 times. In addition to the number, the activity and mobility of MMSCs significantly decreases with age.
As a result of natural aging, diseases, degeneration, injuries, the number and activity of BM-MMSC (bone marrow mesenchymal stromal stem cells) decreases and the body's ability to self-renew worsens. By the age of 50, the number of MMSC decreases by 20 times, by 75 - 100 times. In addition to the number, the activity and mobility of MMSCs significantly decreases with age.
"Factory" MMSC
Therapeutic properties of MMSC
- Pathotropism is the ability to independently find sites of inflammation and cell death in the body and restore damaged areas. When cells die and are damaged, special protein molecules (damage markers) are produced, MMSCs capture these markers and are sent with the blood to the lesions.
- Paracrine effect is the ability to produce more than 100 biologically active substances in 4 directions:
- Cytokines - activate their own local progenitor cells, which form new cells to replace damaged ones.
- Regeneration activators - growth factors, exosomes, anti-fibrotic, anti-apoptotic substances, peptides, external matrix molecules, etc.
- Immunomodulators - relieve inflammation and balance the interaction of the immune system with its own tissues.
- Angioprotectors - stimulate microcirculation and form new capillaries.
MMSC - differences between donor (allogenic) MMSC and one's own (autologous):
1. Donor MMSCs are more active, as they are obtained from younger and absolutely healthy donors.
2. Donor MMSCs have a long-term paracrine effect (the ability to activate one's own local progenitor cells and produce growth factors). One's own MMSCs do not have this effect - they immediately turn into specialized cells to replace damaged ones.
3. Limited period of action - donor MMSCs are active for 30 days, then apoptosis (death of MMSCs) occurs and their remains are utilized by one's own leukocytes.
1. Donor MMSCs are more active, as they are obtained from younger and absolutely healthy donors.
2. Donor MMSCs have a long-term paracrine effect (the ability to activate one's own local progenitor cells and produce growth factors). One's own MMSCs do not have this effect - they immediately turn into specialized cells to replace damaged ones.
3. Limited period of action - donor MMSCs are active for 30 days, then apoptosis (death of MMSCs) occurs and their remains are utilized by one's own leukocytes.
Security and compatibility of MMSC
1. Compatibility - donor MMSCs do not react with the patient's immune system, so they can be administered to any patient. This is due to the presence of a special protein on the surface of MMSCs - MHC-1. There are no cases of immune incompatibility of donor MMSCs during their therapeutic use.
Is there a risk of rejection?
Donor (allogeneic) mesenchymal multipotent stromal cells (MMSCs) do not react with the immune system and, accordingly, do not cause a risk of allergic reactions or rejection.
MMSCs have one important property - the ability to actively interact and change the activity of almost all cells of the immune system (IS), creating an immunotolerant environment for both the MMSCs themselves and the surrounding cells and tissues.
Immunomodulatory properties allow us to consider MMSCs as a safe means of overcoming pathological inflammatory processes and ensuring immune tolerance in organ transplantation and autoimmune diseases. MMSCs are capable of both directly and indirectly (via other cells of the immune system) influencing immune system cells. MMSCs exert their immunomodulatory action through various mechanisms, including secretion of soluble factors and cell-contact interaction with target cells.
2.Safety. MMSCs are not able to multiply and transform in the body. They have only a paracrine effect - they produce growth factors, signaling molecules, etc., which relieve inflammation and activate regeneration. The use of this type of stem cells began in 1996 and until 2025, not a single negative case of their use has been recorded.
Is there a risk of developing cancer?
In 2013, a group of European scientists published a long-term study of the safety of MMSC cell administration procedures used to treat orthopedic problems. In the period 1990-2006, 1873 patients were treated with MMSCs obtained from bone marrow. Patients were monitored from the time of the first administration in 1990 until December 31, 2011 or earlier deaths. Such a long period (an average of 12.5 years in the range of 5-22 years) helped track the possible development of cancer. The primary outcome was to assess the risk of developing tumors at sites treated with MMSCs. The secondary outcome was to show the risk of being diagnosed with cancer at sites not treated with the cells. After reviewing 7,306 MRI images and 52,430 X-rays from 1,873 patients, not a single tumor was found at sites treated with MMSCs.
The study showed no increased risk of developing cancer over a mean follow-up of 12.5 years.
There is no rational reason for the fear, other than that a completely different type of cell (Embryonic stem cell) has the same name (stem cell) but can cause teratomas - hence the confusion!
1. Compatibility - donor MMSCs do not react with the patient's immune system, so they can be administered to any patient. This is due to the presence of a special protein on the surface of MMSCs - MHC-1. There are no cases of immune incompatibility of donor MMSCs during their therapeutic use.
Is there a risk of rejection?
Donor (allogeneic) mesenchymal multipotent stromal cells (MMSCs) do not react with the immune system and, accordingly, do not cause a risk of allergic reactions or rejection.
MMSCs have one important property - the ability to actively interact and change the activity of almost all cells of the immune system (IS), creating an immunotolerant environment for both the MMSCs themselves and the surrounding cells and tissues.
Immunomodulatory properties allow us to consider MMSCs as a safe means of overcoming pathological inflammatory processes and ensuring immune tolerance in organ transplantation and autoimmune diseases. MMSCs are capable of both directly and indirectly (via other cells of the immune system) influencing immune system cells. MMSCs exert their immunomodulatory action through various mechanisms, including secretion of soluble factors and cell-contact interaction with target cells.
2.Safety. MMSCs are not able to multiply and transform in the body. They have only a paracrine effect - they produce growth factors, signaling molecules, etc., which relieve inflammation and activate regeneration. The use of this type of stem cells began in 1996 and until 2025, not a single negative case of their use has been recorded.
Is there a risk of developing cancer?
In 2013, a group of European scientists published a long-term study of the safety of MMSC cell administration procedures used to treat orthopedic problems. In the period 1990-2006, 1873 patients were treated with MMSCs obtained from bone marrow. Patients were monitored from the time of the first administration in 1990 until December 31, 2011 or earlier deaths. Such a long period (an average of 12.5 years in the range of 5-22 years) helped track the possible development of cancer. The primary outcome was to assess the risk of developing tumors at sites treated with MMSCs. The secondary outcome was to show the risk of being diagnosed with cancer at sites not treated with the cells. After reviewing 7,306 MRI images and 52,430 X-rays from 1,873 patients, not a single tumor was found at sites treated with MMSCs.
The study showed no increased risk of developing cancer over a mean follow-up of 12.5 years.
There is no rational reason for the fear, other than that a completely different type of cell (Embryonic stem cell) has the same name (stem cell) but can cause teratomas - hence the confusion!
DOKAR VITA CELLS
We provide a full cycle from specialist consultation to organizing the treatment process in the clinic.
Dokar Vita Cells is an international company whose main activities are:
1. Organization of treatment with cellular products (Al-BM-MMSC, Exosomes, NK cells, oncolytic viruses) of patients from different countries in partner clinics of Russia, Europe, Thailand, Vietnam.
2. Organization of delivery of cellular products (Al-BM-MMSC, Exosomes, NK cells, oncolytic viruses, etc.) from partner laboratories to doctors, clinics and patients.
3. Organization of training of doctors in cellular technologies.
1. Organization of treatment with cellular products (Al-BM-MMSC, Exosomes, NK cells, oncolytic viruses) of patients from different countries in partner clinics of Russia, Europe, Thailand, Vietnam.
2. Organization of delivery of cellular products (Al-BM-MMSC, Exosomes, NK cells, oncolytic viruses, etc.) from partner laboratories to doctors, clinics and patients.
3. Organization of training of doctors in cellular technologies.
Why do you choose us?
-
ExperienceDokar Vita Cells has been operating since 2017 and during this period 2100 patients have received cell therapy. We cooperate with experienced laboratories for the production of cell products in Russia, Europe and Southeast Asia. - Full cycle of treatmentDokar Vita Cells provides a full cycle of therapy, starting with a specialist consultation and ending with post-procedure monitoring.
- ClinicsPartner clinics and hospitals are located in Thailand, Vietnam, Malaysia, Russia, Serbia. All clinics have modern equipment and highly qualified personnel. Patients note comfort and professionalism.
- Free consultationsDuring the consultation, our team of doctors determines the necessity, appropriateness and effectiveness of cell therapy in each specific case, and also develops an individual treatment protocol (dosage, order, preparation, recommendations, etc.)
- MonitoringAfter therapy, we monitor the patient's condition for 6 months. We recommend conducting the minimum necessary studies (compiled individually) and reporting symptoms to our specialist.
- Unique comprehensive programThe cell therapy program is developed individually for each patient (dosage, frequency of administration) and is combined with metabolic and preparatory therapy, and in the case of local injections with taping and DOKAR gymnastics.
First step
to start treatment
Consultation with a specialist
You need to fill out a special form. This information is necessary for the specialist to determine the possibility and appropriateness of cell therapy. Also, based on this data, a personal cell therapy program will be created. The processing may take several days. After that, you will receive a summary with the recommended program, cost, prognosis or refusal with justification. Then you can call or write to the doctor and ask any questions you may have.
консультационная форма Order therapy
1. It is necessary to select the date and place of therapy. Therapy can be ordered no earlier than 14 days before. This is due to the fact that cell products are prepared individually within a week.
2. It is necessary to make an advance payment of 30% of the cost of treatment 7 days before the date of therapy. This is necessary to ensure the guarantee of production of cell products.
3. It is necessary to remember that in case of refusal of therapy, the advance payment is not refundable. This is due to the costs of production of cell products and the impossibility of their storage (MMSCs are stored for 72 hours after production.)
3. The price does not include travel and accommodation
2. It is necessary to make an advance payment of 30% of the cost of treatment 7 days before the date of therapy. This is necessary to ensure the guarantee of production of cell products.
3. It is necessary to remember that in case of refusal of therapy, the advance payment is not refundable. This is due to the costs of production of cell products and the impossibility of their storage (MMSCs are stored for 72 hours after production.)
3. The price does not include travel and accommodation
Treatment
1. The therapy is carried out on an outpatient basis, without hospitalization
2. The treatment procedure lasts 1 hour, is painless, and is well tolerated.
3. It is necessary to take care of arrival at the place of therapy (air tickets, visa) and accommodation (hotel).
4. On the day after the procedure, it is recommended to rest, not to overload yourself with traveling around the city and shopping centers, exclude training, sauna, alcohol, sex.
2. The treatment procedure lasts 1 hour, is painless, and is well tolerated.
3. It is necessary to take care of arrival at the place of therapy (air tickets, visa) and accommodation (hotel).
4. On the day after the procedure, it is recommended to rest, not to overload yourself with traveling around the city and shopping centers, exclude training, sauna, alcohol, sex.
Questions and Answers
Below are typical questions and their answers.
- Question:Is there a risk of developing cancer?Answer:MMSCs are not able to multiply and transform in the body. They have only a paracrine effect - they produce growth factors, signaling molecules, etc., which relieve inflammation and activate regeneration. The use of this type of stem cells began in 1996 and until 2025, not a single negative case of their use has been recorded. Multiple clinical studies have confirmed the oncological safety of mesenchymal stem cells from bone marrow. Oncogenic are embryonic and fetal stem cells, but because of the common name "stem cell" with mesenchymal, there is confusion that all types of stem cells are oncogenic (that is, they provoke the development of cancer). But this is not so. Mesenchymal cells from bone marrow never provoke the development of cancer. This is explained theoretically, confirmed by clinical studies and long-term use (since 1996).
- Question:Are there any long-term negative effects?Answer:The long period of use of mesenchymal stem cells from the bone marrow of young healthy donors and the absence of publications indicate the absolute safety of using this type of stem cells for 30 years
